Synthesis of [18F]flunarizine.
نویسنده
چکیده
Flunarizine, a calcium channel antagonist of the piperazine class, has been labeled with the positron-emitter 18F.4-[18F]Fluoro-4-fluorobenzhydryl chloride was prepared in three steps from no-carrier-added [18F]fluoride ion, and used in the alkylation of N-cinnamylpiperazine to give [18F]flunarizine in 13% radiochemical yield (from [18F]fluoride).
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ورودعنوان ژورنال:
- International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes
دوره 42 2 شماره
صفحات -
تاریخ انتشار 1991